Archived publications for Dr. R. Michael (Mike) Akers

• Lefcourt, A., J. B. Huntington, R.M. Akers, D. L. Wood, and J. Bitman. 1999. Circadian and ultradian rhythms of body temperature and peripheral concentrations of insulin and nitrogen in lactating dairy cows. Domestic Animal Endo. 16:
  41-55.
• Akers, R.M., 1999. Lactogenesis in Encyclopedia of Reproduction, Academic Press Vol 2 37-43.
• Hovey, R.C., T.B. McFadden, and R.M. Akers. 1999. Regulation of mammary gland growth and morphogenesis by mammary fat pad: a species comparison. J. Mammary Gland Biol. Neoplasia 4: 53-68.
• Garst, A.S., S.K. Carlin, J.R. Gibbons, K.W. Kendrick, R.E. Pearson, R.M. Akers, T.L. Bailey, V. H. Velander, H. K. Lubon, and F. C. Gwazdauskas. 1999. In vitro embyro development of good and poor quality bovine oocytes following microinjection of DNA. Transgenics 2: 371-382.
• Capuco, A.V. and R.M. Akers. 1999. Mammary involution in dairy animals. J. Mammary Gland Biology Neoplasia 4: 137-144.
• Weber, M. S., S. Purup, M. Vestergaard, R.M. Akers, and K. S. Sejrsen. 1999. Contribution of IGF-I to mitogenic activity in mammary extracts and serum. J. Endocrinology 161: 365-373.
• Kendrick, K. W., T.L. Bailey, A.S. Garst, A. W. Pryor, A Ahmadzadeh, R.M. Akers, W. E. Eyestone, R. E. Pearson, and F. C. Gwazdauskas. 1999. Effects of energy balance on hormones, ovarian activity and recovered oocytes in lactating Holstein cows using transvaginal follicular aspiration. J. Dairy Sci. 82:1731-1740.
• Barrington, G.M., T.E. Besser, C. C. Gay, W.C. Davis, J.J. Reaves, T.B. McFadden, and R.M. Akers. 1999. Regulation of the immunoglobulin G1 receptor: Effect of prolactin on invivo expression of the bovine mammary immumoglobulin G1 receptor. J. Endocrinology 163:25-31.
• Ellis, S.E., T.B. McFadden, and R.M. Akers. 1998. Prepubertal ovine mammary development is unaffected by ovariectomy. Domestic Animal Endo. 15: 217-225.
• Weber, M.S., P.L. Boyle, B. Corl E.A. Wong, F.C. Gwazdauskas, and R.M. Akers. 1998. Expression of ovine insulin-like growth factor-I (IGF-I) stimulates peripubertal development of alveolar buds in mammary glands of transgenic mice. Endocrine 8: 251-259.
• Akers, R.M., K. Sejrsen, and S. E. Ellis. 1998. Mammary Development: What's It All Mean? Proceedings of 2nd Annual PDHGA National Conference 7-26.
• Maple, R.L., R.M. Akers, and K. Plaut. 1998. Effects of steroid hormone treatment on mammary developemnt in prepubertal heifers. Domestic Animal Endo. 15: 489-498.
• Pan, Y.L., P.K. Bender, R.M. Akers, and K.E. Webb. 1998. One or more serum factors promote peptide utilization in cultured animal cells. J. Nutrition 128: 744-750.
• Capuco, A.V., R.M. Akers, and J.J. Smith 1997. Mammary growth in Holstein cows during the dry period: quantitation of nucleic acids and histology. J. Dairy Sci. 80: 477-487.
• Akers, R.M., K. Sejrsen, Peripubertal Mammary Development and Subsequent Milk Production. 1997. Proceedings Protiva Science Symposium, Dec 9-12, New Orleans 22 pages.
• Rice, R., D. Blodgett, G., Schurig, W. Swecker, J. Fontenot, J. Allen, and R. Akers. 1997. Humoral immune responses of cattle maintained on fescue pastures. Vet. Immunol. Immunopath 59:285-291.
• Akers, R.M. and K. Sejrsen. 1996. Mammary development and milk production. Proceedings NRAES 4: 44-63.
• Pan, Y., P.K. Bender, R.M. Akers, and K.E. Webb. 1996. Methionine-containing peptides as methionine sources for protein accretion in cultured C2C12 and MAC-T cells. J. Nutrition 126:232-241.
• Wang, S., K.E. Webb, and R.M. Akers. 1996. Utilization of peptide-bound methionine for the synthesis of secreted proteins by mammary tissue explants from lactating mice. J. Nutrition 126:1662-1672.
• Ellis, S.E., T.B. McFadden, and R.M. Akers. 1996. Oestrogenic effects on in vitro co-culture of mammary explants and epithelial cells. Proc. New Zealand Soc. Animal Sci. 62-64.
• Purup, S., K. Sejrsen, and R.M. Akers. 1995. Effect of GH and ovariectomy on mammary tissue sensitivity to IGF-I in prepubertal heifers. J. Endocrinology 144: 153-158.
• Politis, I., M.B. Zavizion, J.H. White, J.J. Goldberg, and R.M. Akers. 1995. Hormonal and extracellular matrix regulation of plasminogen activator in a bovine mammary epithelial cell line (MAC-T). Endocrine 3: 345-350.
• Lefcourt, A. M., J. Bitman, D. L. Wood, and R.M. Akers. 1995. Circadian and ultradian rhythms of peripheral growth hormone concentrations in lactating dairy cows. Domestic Animal Endo.12: 247-256.
• Vanderkooi, W.K., M.J. Vanderhaar, B .K. Sharma, M. Binelli, H.A. Tucker, R.M. Akers, and W.M. Moseley. 1995. Comparison of somatotropin releasing factor and somatotropin: the somatotropic axis in lactating primiparous cows. J. Dairy Sci. 78: 2140-2149.
• Romagnolo, D., R.M. Akers, J.C. Byatt, E.A. Wong, and J.D. Turner. 1994. Regulation of expression of IGF-I induced IGFBP-3 and IGF-I receptor by constitutive versus regulated expression of recombinant IGF-I in transfected mammary epithelial cells. Endocrine J. 2: 375-384.
• Morcol, T., R.M. Akers, J.L. Johnson, B.L. Williams, F.C. Gwazdauskas, J.W. Knight, H. Lubon, W.N. Drohan, and W.H. Velander. 1994. A high cell density bioreactor for complex proteins: Expression of human protein C in porcine mammary tissue. Annals New York Academy of Sciences 721: 218-234.
• Romagnolo, D., R.M. Akers, J.C. Byatt, E.A. Wong, and J.D. Turner. 1994. IGF-I - induced IGFBP-3 potentiates the mitogenic actions of IGF-I in mammary epithelial MD-IGF-I cells. Molecular and Cellular Endocrinology 102: 131-139.
• Woodward, T.L., R.M. Akers, and T.D. Turner. 1994. Lack of mitogenic response to EGF, pituitary and ovarian hormones in bovine mammary epithelial cells. Endocrine Journal 2: 579-591.
• Akers, R.M. 1994. Lactation in Encyclopedia of Agricultural Science, Vol 2: 635-643. Academic Press.
• Lefcourt, A.M., R.M. Akers, D.L. Wood, J. Bitman. 1994. Circadian and ultradian rhythms of peripheral prolactin concentrations in lactating dairy cows. Amer. J. Physiology - Regulatory Integrative Comp. Physiol.-36: R1461-R1466.
• Romagnolo, D., R.M. Akers, J.C. Byatt, E.A. Wong. 1994. An in vitro model to study hormonal and substratum regulation of expression of IGF-I linked to the mouse whey acidic acid protein (WAP) gene promoter. Transgenics 1: 399-409.
• Furmura, K., R.M. Akers, and W.E. Beal. 1994. Breed effect on growth of bovine mammary organoids in collagen gel culture. Animal Science Technology 65: 226-238.
• Woodward, T.L., W.E. Beal, and R.M. Akers. 1993. Cell interactions in initiation of mammary epithelial proliferation by oestradiol and progesterone in prebubertal heifers. Journal of Endocrinology 136: 149-157.
• Johnson, D.W., M.A. Barnes, and R.M. Akers. 1993. A synthetic opioid peptide increases plasma growth hormone and prolactin in Holstein calves. J. Animal Sci. 71: 1004-1009.
• Romagnolo, D., R.M. Akers, E.A. Wong, P.L. Boyle, T.B. McFadden, and J.D. Turner. 1993. Lactogenic hormones and extracellular matrix regulate expression of IGF-I linked to MMTV-LTR in mammary epithelial cells. Molecular and Cellular Endocrinology 96: 147-157.
• Purup, S., K. Sejrsen, J. Foldager, and R.M. Akers. 1993. Effect of exogenous bovine growth hormone and ovariectomy on prepubertal mammary growth, serum hormones, and acute in vitro proliferative response of mammary explants from Holstein heifers. J. Endocrinology 139: 19-26.
• Romagnolo, D., R.M. Akers, E.A. Wong, P. L. Boyle, T.B. McFadden, and J.D. Turner. 1992. Overexpression of ovine insulin-like growth factor-I stimulates autonomous autocrine or paracrine growth in bovine mammary derived (MD-IGF-I) epithelial cells. Molecular Endocrinology 6: 1774-1780.
• Zhao, X., B.W. McBride, I. Politis, H.T. Huynh, R.M. Akers, J.H. Burton, and J.D. Turner. 1992. Receptor binding and growth promoting activity of insulin like growth factor I in cultured bovine mammary cells. J. Endocrinology 134: 307-312.
• Akers, R.M. 1991. Lactation physiology: A ruminant animal perspective. Protoplasma 159: 96-111.
• Daniel, T.E., T.B. McFadden and R.M. Akers. 1991. Histological evaluation of ovine mammary tissue xenografted into cyclosporine treated mice. J. Animal Sci. 69: 599-608.
• McFadden, T.B., T.E. Daniel* and R.M. Akers. 1990. Effects of plane of nutrition, growth hormone and unsaturated fat on mammary growth in prepubertal lambs. J. Animal Sci. 68: 3171-3179.
• McFadden, T.B., T.E. Daniel and R.M. Akers. 1990. Effects of plane of nutrition, growth hormone and unsaturated fat on growth hormone, insulin and prolactin receptors in prepubertal lambs. J. Animal Sci. 68: 3180-3189.
• Capuco, A.V. and R.M. Akers. 1990. 3H Thymidine incorporation by lactating mammary epithelium during compensatory mammary growth in beef cattle. J. Dairy Sci. 73: 3094- 3103.
• Akers, R.M., W.E. Beal, T.B. McFadden and A.V. Capuco. 1990. Morphometric analysis of involuting bovine mammary tissue after 21or 42 days of non suckling. J. Animal Sci. 68: 3604-3613.
• Smith, J.J., A.V. Capuco, W.E. Beal, and R.M. Akers. 1989. Association of prolactin and insulin receptors with mammogenesis and lobulo alveolar formation in pregnant ewes. International J. Biochemistry 21: 73-89.
• Sordillo, L.M., S.C. Nickerson, and R.M. Akers. 1989. Pathology of Staphyococcus aureus mastitis during lactogenesis: relationships with bovine mammary structure and function. J. Dairy Sci. 72: 228-240.
• Akers, R.M. and R.M. Kaplan*. 1989. Role of milk secretion on transport of prolactin from blood into milk. Hormone Res. 21: 362-365.
• Perera, K.S., F.C. Gwazdauskas, R.M. Akers, and M.L. McGilliard. 1989. Effect of supplemental light on growth, prolactin, progesterone, and luteinizing hormone in water buffalo (Bubalus bubalis). International Journal of Biometerology 31: 154-161.
• McFadden, T.B., R.M. Akers and W.E. Beal. 1989. Influence of breed and hormones on production of milk proteins by mammary explants from prepubertal heifers. J. Dairy Sci. 72: 1754-1763.
• Keys, J.E., A.V. Capuco, R.M. Akers, and J. Djiane. 1989. Comparative study of mammary gland development and differentiation between beef and dairy heifers. Domestic Animal Endo. 6: 311-319.
• Nickerson, S.C., W.J. Thompson*, S.P. Oliver, and R.M. Akers. 1988. Effect of an intramammary bead device on leucocyte count, lacteal secretion composition, and incidence of mastitis during the non lactating period. Amer. J. Vet. Res. 49: 1205 1209.
• McFadden, T.B., R.M. Akers, and W.E. Beal. 1988. Milk protein secretion by explants of prepuberal bull mammary tissue: genetic effects. J. Dairy Science 71: 2904 2914.
• Baumrucker, C.R., K.P. Deemer, R. Walsh, T.L. Riss, and R.M. Akers. 1988. Primary culture of bovine mammary acini on a collagen matrix. Tissue and Cell 20: 541-554.
• McFadden, T.B., R.M. Akers, and A.V. Capuco. 1988. Relationships of milk proteins in blood with somatic cell counts in milk of dairy cows. J. Dairy Sci. 71: 826-834.
• McFadden, T.B., R.M. Akers, and G.W.Kazmer. 1987. Alpha lactalbumin in bovine serum: relationships with udder development and function. J. Dairy Sci. 70: 259-264.
• Smith, J.J., A.V. Capuco, and R.M. Akers. 1987. Quantification of progesterone binding in mammary tissue of pregnant ewes. J. Dairy Sci. 70: 1178-1185.
• Akers, R.M. and W. Thompson. 1987. Effect of induced leucocyte migration on mammary cell morphology and milk component biosynthesis. J. Dairy Sci. 70: 1685-1695.
• Akers, R.M., T.B. McFadden, W.E. Beal, A.J. Guidry, and H.M.Farrell. 1986. Radioimmunoassay for measurement of bovine alpha lactalbumin in serum, milk and culture media. J. Dairy Research 53: 419-429.
• Kazmer, G.W., M.A. Barnes, R.M. Akers, and W.D. Whittier. 1986. Lactogenic hormone receptors in mammary membrane preparations from periparturient, 60 and 180 days postpartum Holstein cattle. J. Endocrinology 109: 175-180.
• Sejrsen, K., J. Foldager, M.T. Sorensen, R.M. Akers, and D.E. Bauman. 1986. Effect of exogenous bovine somatotropin on pubertal mammary development in heifers. J. Dairy Sci. 69: 1528-1535.
• Akers, R.M. and J. E. Keys. 1985. Effect of suckling intensity on lactogenic hormone binding, biochemical composition and histological characteristics of ovine mammary glands. Domestic Animal Endocrinology 2: 159-172.
• Akers, R.M. 1985. Lactogenic hormones: binding sites, mammary growth, secretory cell differentiation and milk biosynthesis in ruminants. J. Dairy Sci. 68: 501-519.
• Nickerson, S.C. and R.M. Akers. 1984. Biochemical and ultrastructural aspects of milk synthesis and secretion. International Journal Biochemistry 16: 855-865.
• Akers, R.M. and A.M. Lefcourt. 1984. Effect of presence of the calf on milking induced release of prolactin and oxytocin during early lactation in dairy cows. J. Dairy Sci. 67: 115-122.
• Goodman, G.T., R.M. Akers, K.H. Friderici, and H.A. Tucker. 1983. Hormonal regulation of alpha-lactalbumin secretion from bovine mammary tissue cultured in vitro. Endocrinology 112: 1324-1330.
• Akers, R.M. and S.C. Nickerson. 1983. Effect of prepartum blockade of microtubule formation on milk production and biochemical differentiation of the mammary epithelium in Holstein heifers. International J. Biochemistry 15: 771-775.
• Nickerson, S.C. and R.M. Akers. 1983. Effect prepartum blockade of microtubule formation on ultrastructural differentiation of the mammary epithelium in Holstein heifers. International J. Biochemistry 15: 777-788.
• Sejrsen, K., J.T. Huber, H.A. Tucker, and R.M. Akers. 1982. Influence of plane of nutrition on mammary development in pre and post pubertal heifers. J. Dairy Sci. 65: 793-800.
• Akers, R.M. and A.M. Lefcourt. 1982. Teat stimulation induced prolactin release in non pregnant and pregnant Holstein heifers. J. Endocrinology 96: 433-442.
• Akers, R.M. and A.M. Lefcourt. 1982. Milking and suckling induced secretion of oxytocin and prolactin in parturient dairy cows. Hormones and Behavior 16: 87-93.
  
• Akers, R.M., G.T. Goodman, and H.A. Tucker. 1980. Clearance and secretion rates of prolactin in dairy cattle in various physiological states. Proc. Soc. Exp. Biol. Med. 164: 115 119.
• Akers, R.M., D.E. Bauman, A.V. Capuco, G.T. Goodman, and H.A. Tucker. 1981a. Prolactin regulation of milk secretion and biochemical differentiation of mammary epithelial cells in periparturient cows. Endocrinology 109: 23-30.
• Akers, R.M., D. E. Bauman, G. T. Goodman, A. V. Capuco, and H. A.Tucker. 1981b. Prolactin regulation of cytological differentiation of mammary epithelial cells in periparturient cows. Endocrinology 109: 31- 40.
• Akers, R.M. and C.W. Heald. 1978. Effect of removal of prepartum secretions on secretory cell differentiation in the bovine mammary gland. J. Ultrastructure Research 63: 316-322.
• Akers, R.M., C.W. Heald, T .L. Bibb, and M.L. McGilliard. 1977. Effect of prepartum milk removal on quantitative morphology of bovine lactogenesis. J. Dairy Sci. 60: 1273-1282.